Welcome

The Bingel Laboratory

Translational Pain Research Unit

University Medicine Essen
Prof. Dr. Ulrike Bingel

Logo-UME_web_DE_100px_height
UK-Essen_Neurologie_Logo_20170727
C-TNBS_acronym Kopie
SFB289_Logo_Farbe
SFB1280_Logo_Farbe

The Bingel Laboratory

Gruppenfoto

Prof. Dr. Ulrike Bingel and her research group focuses on the interaction between pain and cognitive processes. We have a longstanding expertise in investigating the CNS mechanisms underlying nociception, pain, and pain modulation in health and disease. In our research, we use behavioural paradigms, pharmacological modulations, as well as functional and structural brain imaging. Being particularly intrigued by the reciprocal effects of pain and cognition, we have a strong focus on translational questions such as the role of expectations and prior experiences on analgesic treatment outcomes. Our interdisciplinary research group comprises neurologists, neuroscientists, psychologists, biologists, and computer scientists and is based at the Department of Neurology at the University Medicine Essen. We are affiliated with the Erwin-L-Hahn institute for magnetic resonance imaging and the Translational Pain Research Department of the University Pain Center. Our research is funded by the Deutsche Forschungsgemeinschaft.

Recent News

New publication: Open-label placebos and academic test performance; a secondary analysis.
10th October 2025

The study “The association between test anxiety, learning strategies, and open-label placebo effects on academic test performance” presents a secondary analysis of a randomized controlled trial. Elisa Frisaldi examined whether test anxiety and individual learning strategies moderate the effects of open-label placebos (OLPs) on academic performance. The results suggest that students with higher levels of test anxiety achieved better exam outcomes in the OLP group compared to the control group. Moreover, cognitive, metacognitive, and resource-related learning strategies appeared to interact with the placebo effect. The authors emphasize the need for further studies to confirm and extend these findings. Read the full publication

Visitors from Düsseldorf!
10th October 2025

It was a great pleasure to have Susanne Becker and Lisa Garcia from Heinrich-Heine-University Düsseldorfin our group meeting today! There new data, planned studies, and a lot of time for discussions about shared interests and potential collaborations! More information on Susanne's research group can be found here.

In the picture from left to right: Katharina Schmidt, Ulrike Bingel, Susanne Becker, Lisa Garcia, Sigrid Elsenbruch, and Adriane Icenhour.

New Publication: Predictors of Objective Improvements After Open-Label Placebo in Chronic Back Pain
25th September 2025

In a recently published exploratory analysis of our randomized controlled trial, Elif Caliskan and members of our team examined whether psychological and physiological factors predict objective improvements (spinal mobility) after OLP treatment combined with treatment-as-usual. The results indicate that patients with lower pain catastrophizing benefited most, showing increased spinal motion velocity, while those with higher catastrophizing did not. These findings highlight that OLPs may provide measurable benefits for specific patient subgroups, pointing toward the potential of personalized pain medicine. Further studies are needed to confirm these results and to better understand the role of psychological factors in chronic pain management. Read the full publication

New publication in Collabra
3rd September 2025

A new perspective piece led by Helena Hartmann details the many ways in which we cna use feminist approaches in our own research. Feminism is about all forms of challenging social, economic and political power taken by a dominant group. Applying a feminist lens to scientific research can bring many advantages. The paper functions as an access point for (1) why researchers should incorporate feminist approaches in psychological science, (2) what feminist approaches could look like and (3) how researchers can start incorporating them into their own work. Find out more about the Feminist Wonder Lab and read the full article published in Collabra: Psychology.

Bingel_logo_ENG

The Bingel Laboratory

Prof. Dr. med. Ulrike Bingel

Clinical Neurosciences
University Hospital Essen
Department of Neurology

Hufelandstraße 55
45147 Essen
Germany
Fon: +49 (0) 201 723 - 2446
Fax: +49 (0) 201 723 - 6882
Mail: ulrike.bingel@uk-essen.de

Copyright 2021 - Bingel Laboratory