The Bingel Laboratory

Prof. Dr. Ulrike Bingel and her research group focuses on the interaction between pain and cognitive processes. We have a longstanding expertise in investigating the CNS mechanisms underlying nociception, pain, and pain modulation in health and disease. In our research, we use behavioural paradigms, pharmacological modulations, as well as functional and structural brain imaging. Being particularly intrigued by the reciprocal effects of pain and cognition, we have a strong focus on translational questions such as the role of expectations and prior experiences on analgesic treatment outcomes. Our interdisciplinary research group comprises neurologists, neuroscientists, psychologists, biologists, and computer scientists and is based at the Department of Neurology at the University Medicine Essen. We are affiliated with the Erwin-L-Hahn institute for magnetic resonance imaging and the Translational Pain Research Department of the University Pain Center. Our research is funded by the Deutsche Forschungsgemeinschaft.
Recent News

We are currently looking for support with our experimental studies in Essen, particularly with MRI measurements but also general research assistant tasks. Feel free to download and forward this ad to interested parties here. If you have any questions, feel free to reach out to Katarina Forkmann (katarina.forkmann@uk-essen.de).

Helena Hartmann and colleagues systematically reviewed 50/2060 screened studies that looked at how changing someone’s own pain experience — through substances like opioids, acetaminophen, cannabinoids, placebos, alcohol, or hypnosis — also affects how people feel and respond to others’ emotions and pain. The authors found mixed and inconsistent effects, meaning some types of pain modulation sometimes increased or decreased social cognition abilities, with the most consistent and replicated result being that placebo analgesia reduced empathy for others’ pain. However, because the studies were very different from each other and often had small sample sizes or specific study designs, a lot more work is needed to understand how our own pain influences social feelings and behavior overall. Read the full publication in the journal Pain here.

A new (German) podcast episode from the ERCM Medizin Podcast with Ulrike Bingel talks about the power of expectations, its neurobiological mechanisms, doctor-patient communication and the importance of trust in this relationship! Watch the full episode here.

Today we have something about science communication! This new (German) book is aimed at healthcare professionals, so everyone working with or around patients: How can you use placebo effects when working with patients? How can you harness the power of expectation in patient care? How can you communicate successfully?
Order and read it here as a physical copy or ebook.
